Nicholas Tzikas, MD, MPHHeadache & Facial Pain Medicine

A structured care initiative

The Headache Project

Headache care run on a target and a timeline.

Treatment is a process, not a single appointment. The Headache Project is the umbrella for programs designed around active management, planned reassessment, and coordinated care.

01
Target
02
Timeline
03
The plan

The problem

Good treatment can fail when the next decision comes too late.

A preventive medication often needs about two months at an adequate dose before its effect can be judged. Many patients need more than one adjustment. When follow-up is delayed for months, side effects go unaddressed, ineffective plans continue, and the next visit can feel like starting over.

Other fields use a treat-to-target model: define the outcome, measure progress, and adjust at planned intervals. The Headache Project applies that operating discipline to specialized headache care while keeping every decision individualized.

The differentiator is not access to a different medication. It is what happens between the first prescription and the result.

The operating model

A target. A decision date. A plan that keeps moving.

01

The target

A number set at the beginning.

The plan starts with a documented treatment target, informed by headache frequency and the effect headaches have on work and life. A 50% reduction in headache days is a commonly used benchmark for preventive response, interpreted in the context of the individual patient.

02

The decision date

A date for the next decision.

Preventive treatment takes time to judge. The next decision point is established in advance, so a plan can continue, adjust, or change when the treatment has had an adequate opportunity to work.

03

The plan

One plan, whoever is involved.

The target and the timeline belong to the plan, not to a single appointment. Care may involve other providers as treatment evolves, and the plan is what keeps decisions connected instead of losing momentum between disconnected appointments.

Two pathways

Get better. Then stay better.

Program structure and enrollment details are being finalized. The overview below describes the intended clinical purpose, not a fixed schedule or package of services.

Year one pathway

Headache Reset

Goal: Get better

A structured first year centered on treatment optimization, medication titration, side-effect management, troubleshooting, and ongoing reassessment against a defined target.

Enrollment details coming soon.

Ongoing pathway

Headache Maintenance

Goal: Stay better

Continued reassessment after the initial treatment phase, designed to protect progress, revisit the plan as needs change, and keep long-term care intentional.

Enrollment details coming soon.

A consultation space for structured headache treatment planning
Every pathway begins with diagnosis, an individualized plan, and a documented measure of progress.

What a first year is designed to do

  1. 01

    Consultation

    Confirm the diagnosis, define the target, and map the next treatment decisions.

  2. 02

    Early phase

    Reach the intended treatment plan, address tolerability, and make the first decision on time.

  3. 03

    Reassessment

    Measure progress against the original target and adjust when the result falls short.

  4. 04

    Long-term plan

    Read the year against the starting measure and establish what should happen next.

A distinct program

Connected to interventional expertise, but not defined by it.

The Headache Project is focused on active headache management. The practice's CSF and vascular headache work is a separate clinical pathway for patients whose history or imaging raises questions about pressure, venous outflow, or another neurovascular cause.

A patient may need one pathway, both, or neither. When the questions overlap, care can be coordinated within the same interventional neurology practice without turning every headache into an interventional problem.

Patients with a pressure or vascular question are seen in the CSF and Vascular Headache Clinic.

Explore the CSF & vascular headache program →

Program interest

Start with a consultation.

Headache Reset and Headache Maintenance are being developed at the Center for Interventional Headache Medicine. Enrollment details are coming soon.

Manhattan

57 W 57th St, Suite 1406
New York, NY 10019

Midtown · near Sixth Avenue

Get directions ↗

East Hills · Long Island

2200 Northern Blvd, Suite 207
East Hills, NY 11576
Get directions ↗

Selected references

  1. 1. Ailani J, Burch RC, Robbins MS. American Headache Society Consensus Statement: integrating new migraine treatments into clinical practice. Headache. 2021;61(7):1021–1039.
  2. 2. Grigor C, Capell H, Stirling A, et al. Effect of a treatment strategy of tight control for rheumatoid arthritis: the TICORA study. Lancet. 2004;364(9430):263–269.
  3. 3. Smolen JS, Breedveld FC, Burmester GR, et al. Treating rheumatoid arthritis to target: 2014 update. Ann Rheum Dis. 2016;75(1):3–15.

These references support the clinical benchmarks and treat-to-target rationale. The Headache Project itself is a practice program, not a clinical trial. Information here is general and does not replace individualized medical advice.